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What is Barrett's esophagus? What causes Barrett's esophagus? What is gastroesophageal reflux disease (GERD)? Who gets Barrett's esophagus? How do I know for sure if I have Barrett's? Is there a cure for my Barrett's esophagus?
Do we know how cancer develops in Barrett's? If I have Barrett's, will I get cancer? What are the treatment options for high-grade dysplasia in Barrett's? What are the treatment options for cancer in Barrett's? What are some non-surgical therapies for Barrett's?
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What are some non-surgical or investigational therapies for Barrett's esophagus?
Anderson WF. Gene therapy scores against cancer [news; comment]. Nature Medicine 2000; 6(8):862-3.
Barr H. Barrett's esophagus: treatment with 5-aminolevulinic acid photodynamic therapy. Gastrointestinal Endoscopy Clinics of North America 2000; 10(3):421-37.
Berenson MM, Johnson TD, Markowitz NR, Buchi KN, Samowitz WS. Restoration of squamous mucosa after ablation of Barrett's esophageal epithelium. Gastroenterology 1993; 104(6):1686-91.
Biddlestone LR, Barham CP, Wilkinson SP, Barr H, Shepherd NA. The histopathology of treated Barrett's esophagus: squamous reepithelialization after acid suppression and laser and photodynamic therapy. American Journal Of Surgical Pathology 1998; 22(2):239-45.
Buttar NS, Wang KK, Sebo TJ, Riehle DM, Krishnadath KK, Lutzke LS, Anderson MA, Petterson TM, Burgart LJ. Extent of high-grade dysplasia in Barrett's esophagus correlates with risk of adenocarcinoma. Gastroenterology 2001; 120(7):1630-9.
Corley DA, Kerlikowske K, Verma R, Buffler P. Protective association of aspirin/NSAIDS and esophageal cancer: a systematic review and meta-analysis. Gastroenterology, 2003; 124(1):47-56.
Dulai GS, Jensen DM, Cortina G, Fontana L, Ippoliti A. Randomized trial of argon plasma coagulation vs. multipolar electrocoagulation for ablation of Barrett's esophagus. Gastrointestinal Endoscopy 2005;61:232-40.
Ell C, May A, Gossner L, Pech O, Gunter E, Mayer G, Henrich R, Vieth M, Muller H, Seitz G, Stolte M. Endoscopic mucosal resection of early cancer and high-grade dysplasia in Barrett's esophagus. Gastroenterology 2000; 118(4):670-7.
Eisen G. Ablation therapy for Barrett's esophagus. Gastrointestinal Endoscopy 2003; 58:760-8.
Falk G. Unresolved issues in Barrett's esophagus in the new millennium. Digestive Diseases 2000; 18(1):27-42.
Ganz RA, Utley DS, Stern RA, Jackson J, Batts KP, Termin. Complete ablation of esophageal epithelium with a balloon-based bipolar electrode: a phased evaluation in the porcine and in the human esophagus. Gastrointestinal Endoscopy, 2004;60(6):1002-10).
Garewal H, Ramsey L, Sharma P, Kraus K, Sampliner R, Fass R. Biomarker studies in reversed Barrett's esophagus. American Journal of Gastroenterology 1999; 94(10):2829-33.
Gross CP, Cruz_Correa M, Canto MI, McNeil_Solis C, Valente TW, Powe NR. The adoption of ablation therapy for Barrett's esophagus: a cohort study of gastroenterologists. The American Journal of Gastroenterology 2002; 97(2):279-86.
Hage M, Siersema PD, Vissers KJ, et al. Genomic analysis of Barrett's esophagus after ablative therapy: Persistence of genetic alterations at tumor suppressor loci.International Journal of Cancer. 2005. 
Johnston MH, Eastone JA, Horwhat JD, Cartledge J, Mathews JS, Foggy JR. Cryoablation of Barrett's esophagus: a pilot study. Gastrointestinal Endoscopy 2005; 62:842-8.
Johnston MH. Cryotherapy and other newer techniques. Gastrointestinal Endoscopy Clinics of North America, 2003; 13(3):491-504.
Johnston CM, Schoenfeld LP, Mysore JV, Dubois A. Endoscopic spray cryotherapy: a new technique for mucosal ablation in the esophagus. Gastrointestinal Endoscopy 1999; 50(1):86-92.
Kelty, CJ, Ackroyd R, Brown NJ, Brown SB, Reed MW. Comparison of high-vs low-dose 5-aminolevulinic acid for photodynamic therapy of Barrett's esophagus. Surgical Endoscopy, 2004. 18(3):p452-8.
Khuri FR, Nemunaitis J, Ganly I, Arseneau J, Tannock IF, Romel L, Gore M, Ironside J, MacDougall RH, Heise C, Randlev B, Gillenwater AM; Bruso P, Kaye SB, Hong WK, Kim DH.. a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer [see comments]. Nature Medicine 2000; 6(8):879-85.
Krishnadath KK, Wang KK, Taniguchi K, Sebo TJ, Buttar NS, Anderson MA, Lutzke LS, Liu W. Persistent genetic abnormalities in Barrett's esophagus after photodynamic therapy. Gastroenterology 2000; 119(3):624-30.
Lambert R. Endoscopic mucosectomy: an alternative treatment for superficial esophageal cancer. Recent Results in Cancer Research 2000; 155:183-92.
Lim KN, Waring PJ, Saidi R. Therapeutic options in patients with Barrett's esophagus. Digestive Diseases 1999; 17(3):145-52.
May A, Gossner L, Pech O, Fritz A, Gunter E, Mayer G, Muller H, Seitz G, Vieth M, Stolte M, and Ell C, Local endoscopic therapy for intraepithelial high-grade neoplasia and early adenocarcinoma in Barrett's oesophagus: acute-phase and intermediate results of a new treatment approach. European Journal of Gastroenterology & Hepatology, 2002. 14(10): p. 1085-91.
Nijhawan PK, Wang KK. Endoscopic mucosal resection for lesions with endoscopic features suggestive of malignancy and high-grade dysplasia within Barrett's esophagus [see comments]. Gastrointestinal Endoscopy 2000; 52(3):328-32.
Overholt BF, Lightdale CJ, Wang KK et al. Photodynamic therapy with porfimer sodium for ablation of high-grade dysplasia in Barrett's esophagus: international, partially blinded, randomized phase III trial. Gastrointestinal Endoscopy, 2005,62(4);488-498. 
Editorial (Pro): See Wolfsen HC below
Editorial (Con): See Siersema PD below
Overholt BF, Panjehpour M, Halberg DL. Photodynamic therapy for Barrett's esophagus with dysplasia and /or early stage cancer. Gastrointestinal Endoscopy, 2003, 58(2); 183-8.
Overholt BF, Panjehpour M, Haydek JM. Photodynamic therapy for Barrett's esophagus: follow-up in 100 patients. Gastrointestinal Endoscopy 1999; 49(1):1-7.
Pacifico, RJ, Wang KK, Wongkeesong LM, Buttar NS, Lutzke LS. Combined endoscopic mucosal resection and photodynamic therapy versus esophagectomy for management of early adenocarcinoma in Barrett's esophagus. Clinical Gastroenterology and Hepatology, 2003. 1 (4):p252-257.
Panjehpour M, Overholt BF, Phan NM, Haydek JM. Optimization of light dosimetry for photodynamic therapy of Barrett's esophagus: efficacy vs. incidence of stricture after treatment. Gastrointestinal Endoscopy. 2005, 61(1); 13-8.
Pech O, Gossner L, May A, Rabenstein T, Vieth M, Stolte M, Berres M, Ell C. Long-term results of photodyamic therapy with 5-aminolevulinic acid for superficial Barrett's cancer and high-grade intraepithelial neoplasia. Gastrointestinal Endoscopy 2005; 62(1): 24-30.
Pereira-Lima JC, Busnello JV, Saul C, Toneloto EB, Lopes CV, Rynkowski CB, Blaya C. High power setting argon plasma coagulation for the eradication of Barrett's esophagus. American Journal of Gastroenterology 2000; 95(7):1661-8..
Sampliner RE, Faigel D, Fennerty MB, Lieberman D, Ippoliti A, Lewin K, Weinstein WM. Effective and safe endoscopic reversal of nondysplastic Barrett's esophagus with thermal electrocoagulation combined with high-dose acid inhibition: a multicenter study. Gastrointestinal Endoscopy 2001; 53(6):554-8.
Sampliner RE. Ablation of Barrett's mucosa. Gastroenterologist 1997; 5(3):185-8.
Sampliner RE. Ablative therapies for the columnar-lined esophagus. Gastroenterol Clin North Am 1997; 26(3):685-94.
Schulz H, Miehlke S, Antos D, Schentke KU, Vieth M, Stolte M, Bayerdorffer E. Ablation of Barrett's epithelium by endoscopic argon plasma coagulation in combination with high-dose omeprazole. Gastrointestinal Endoscopy 2000; 51(6):659-63.
Seewald, S et al. Circumferential EMR and complete removal of Barrett's epithelium: a new approach ot management of Barrett's esophagus containing high-grade intraepithelial neoplasia and intramucosal carcinoma. Gastrointestinal Endoscopy, 2003.57(7):p.854-9
Sharma P, Bhattacharyya A, Garewal HS, Sampliner RE. Durability of new squamous epithelium after endoscopic reversal of Barrett's esophagus. Gastrointest Endosc 1999; 50(2):159-64.
Sharma P, Jaffe PE, Bhattacharyya A, Sampliner RE. Laser and multipolar electrocoagulation ablation of early Barrett's adenocarcinoma: long-term follow-up. Gastrointestinal Endoscopy 1999; 49(4 Pt 1):442-6.
Siersema PD. Photodynamic therapy for Barrett's esophagus: not yet ready for the premier league of endoscopic interventions. Gastrointestinal Endoscopy, 2005,62(4);503-507.
van den Boogert J, van Hillegersberg R, Siersema PD, de Bruin RW, Tilanus HW. Endoscopic ablation therapy for Barrett's esophagus with high-grade dysplasia: a review. American Journal of Gastroenterology 1999; 94(5):1153-60.
van Laethem JL, Cremer M, Peny MO, Delhaye M, Devire J. Eradication of Barrett's mucosa with argon plasma coagulation and acid suppression: immediate and mid term results [see comments]. Gut 1998; 43(6):747-51.
van Laethem JL, Peny MO, Salmon I, Cremer M, Deviere J. Intramucosal adenocarcinoma arising under squamous re-epithelialisation of Barrett's esophagus. Gut 2000; 46(4):574-7
Wang KK. Current status of photodynamic therapy of Barrett's esophagus. Gastrointest Endosc 1999; 49(3 Pt 2):S20-3.
Wang KK. Photodynamic therapy of Barrett's esophagus. Gastrointestinal Endoscopy Clinics of North America 2000; 10(3):409-19.
Wolfsen HC. Carpe Luz-seize the light: endoprevention of esophageal adenocarcinoma when using photodynamic therapy with porfimer sodium. Gastrointestinal Endoscopy, 2005,62(4);499-503. 
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